Smith & Nephew Plc - Holding(s) in Company

(Marketwire Via Acquire Media NewsEdge) LONDON, September 24 / MARKET WIRE/ --

NOTIFICATION OF MAJOR INTERESTS IN SHARES

1. Name of company

Smith & Nephew plc

2. Name of shareholder having a major interest

Legal & General Group plc

3. Please state whether notification indicates that it is in
respect of
holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if
it is
a holding of that person's spouse or children under the age of 18

Non-beneficial

4. Name of the registered holder(s) and, if more than one holder,
the
number of shares held by each of them

Legal & General Assurance (Pensions Management) Limited (PMC)

Legal & General Group Plc (L&G)

...............................

5. Number of shares / amount of stock acquired

6. Percentage of issued class

7. Number of shares / amount of stock disposed

8. Percentage of issued class

9. Class of security

Ordinary shares of US 20 cents

10. Date of transaction

19.09.2008

11. Date company informed

22.09.2008

12. Total holding following this notification

40,039,665

13. Total percentage holding of issued class following this
notification

4.53%

14. Any additional information

..............................

15. Name of contact and telephone number for queries

Gemma Parsons - Assistant Company Secretary

020 7960 2228

16. Name and signature of authorised company official responsible
for
making this notification

Gemma Parsons - Assistant Company Secretary

Date of notification

24.09.2008

The FSA does not give any express or implied warranty as to the
accuracy of this document or material and does not accept any
liability
for error or omission. The FSA is not liable for any damages
(including, without limitation, damages for loss of business or
loss of
profits) arising in contract, tort or otherwise from the use of or
inability to use this document, or any material contained in it,
or
from any action or decision taken as a result of using this
document or
any such material.

This information is provided by RNS
The company news service from the London Stock Exchange

END

Contacts:
RNS
Customer
Services
0044-207797-4400Email Contacthttp://www.rns.com

Copyright ? 2008 Marketwire

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